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Variables
|
MDD1
|
Control
|
P value
|
|---|
|
Number
|
54
|
37
|
–
|
|
Age (year)a
|
42.4 ± 14.7
|
39.4 ± 7.0
|
P = 0.187†
|
|
Body mass index (kg/m2)a
|
24.2 ± 3.1
|
24.0 ± 3.5
|
P = 0.661†
|
|
Smoker/non smoker
|
13 / 41
|
5 / 32
|
P = 0.214‡
|
|
HbA1c (%)a4
|
5.4 ± 0.5
|
5.4 ± 0.8
|
P = 0.970†
|
|
Cortisol (μg/dl)a
|
12.1 ± 4.8
|
11.1 ± 3.0
|
P = 0.191†
|
|
DHEAS (μg/dl)a2
|
227.9 ± 108.4
|
307.4 ± 131.2
|
P = 0.002†
|
|
Cortisol / DHEAS ratioa
|
0.07 ± 0.05
|
0.04 ± 0.02
|
P = 0.001†
|
|
IGF1 (ng/ml)a3
|
171.5 ± 61.8
|
144.1 ± 39.2
|
P = 0.011†
|
|
Testosterone (ng/ml)a
|
5.0 ± 1.6
|
4.9 ± 1.6
|
P = 0.709†
|
|
Estradiol (pg/ml)a
|
22.4 ± 8.4
|
26.1 ± 8.5
|
P = 0.040†
|
- aData are expressed as the mean ± standard deviation. †Unpaired t-test. ‡Chi-squared tests. Abbreviations: 1MDD Major depressive disorder, 2DHEAS Dehydroepiandrosterone and its sulfate, 3IGF1 Insulin-like growth factor 1, 4HbA1c Glycated hemoglobin
