Table 1 Demographic characteristics and genotypes of the study population
From: Effect of CYP2D6 polymorphisms on plasma concentration and therapeutic effect of risperidone
| Total study population (n = 76) | |
|---|---|
| Sex (male/female) | 38/38 |
| Age (years) | 45.0 (33.0, 54.0) |
| Height (cm) | 164.5 (158.0, 171.0) |
| Weight (kg) | 65.5 (56.3, 74.5) |
| BMI | 23.3 (21.4, 27.9) |
| Dose (mg) | 5.0 (4.0, 6.0) |
| PANSS | 88.0 (82.0, 95.0) |
| BPRS | 45.5 (41.3, 50.8) |
| CGI-S (2 week) | 5.0 (5.0, 6.0) |
| CGS-I (2 week) | 3.0 (3.0, 4.0) |
| Mutation sites | |
| 100 (C > T) | 62 (81.6) |
| 1038 (C > T) | 62 (81.6) |
| 1662 (G > C) | 68 (89.5) |
| 2851 (C > T) | 20 (26.3) |
| 4181 (G > C) | 71 (93.4) |
| Genotypes | |
| CYP2D6*10 | 47 (81.6) |
| CYP2D6*2 | 7 (9.2) |
| CYP2D6*65 | 13 (17.1) |